Monday, March 1, 2021

Nutrition disparities during the COVID-19 pandemic

 - Jennifer Middleton, MD, MPH

A large, multi-year study of nutrition habits in France is yielding interesting findings during the COVID-19 pandemic. Behaviors related to nutrition are no exception to the deep-seated health inequities COVID-19 continues to expose.

The Nutri-Net Sante study began in 2009. Study researchers monitor participants using a sophisticated online survey:

[D]ietary intakes are assessed every 6 months as part of the usual cohort follow-up using three non-consecutive 24 [hour] dietary records randomly assigned over two weeks and including two weekdays and one weekend day. These web-based 24 [hour] dietary records have been validated against dietary records filled during an interview with a dietitian and against biomarkers.

In April 2020, during France's nationwide lockdown, the researchers collected data from participants regarding changes in lifestyle habits. While some participants increased their snacking frequency (an otherwise rarity in French culture) and decreased their physical activity, others instead increased their home cooking of nutritious meals and increased their physical activity. The less healthy behaviors correlated with lower socio-economic status (SES), while the more healthy behaviors correlated with higher SES.

Although these findings have yet to be formally peer-reviewed and published, they are consistent with similar studies across the globe (ItalyPolandChinaLatin America). The Centers for Disease Control and Prevention (CDC) recommends "good nutrition" to build resilience during the pandemic; they acknowledge, however, that achieving this aim is challenging for many by also listing resources regarding food insecurity. Google searches related to food insecurity ("food bank," "free food") have increased world-wide since March 2020. "The health disparities in nutrition and obesity correlate closely with the alarming racial and ethnic disparities related to Covid-19.

During the COVID-19 pandemic, it's more critical than ever that we systematically and universally screen our patients for food insecurity along with other social determinants of health. Several simple screening tools exist, including the AAFP's EveryONE Project's Social Needs Screening Tool. The EveryONE Project website also includes guidance for connecting patients with community resources. This 2018 AFP editorial on "Food Insecurity: How You Can Help Your Patients" also includes a comprehensive list of online tools and resources. 

Post-pandemic, we must support improvements in our social environment that will mitigate long-standing racial biases and provide equitable health for all; this equity cannot be achieved without access to affordable and high-quality nutrition for all persons. The COVID-19 pandemic is a powerful reminder that efforts to improve our patients' health and well-being will always be incomplete if we confine them to the interiors of hospitals, health centers, and physicians' offices.

Tuesday, February 23, 2021

Immunization and immunotherapy updates for family physicians

 - Kenny Lin, MD, MPH

The Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices (ACIP) 2021 Adult and Child/Adolescent Immunization Schedules included a number of key updates that are discussed in the February 15 issue of AFP. The schedules included information on the two messenger RNA vaccines against SARS-CoV-2 that have received Emergency Use Authorization from the U.S. Food and Drug Administration (FDA): the Pfizer-BioNTech vaccine for persons older than 16 years and the Moderna vaccine for persons older than 18 years. As Dr. Jennifer Middleton noted in a previous blog post, additional vaccines with different mechanisms may become available in the U.S. soon; data on the Janssen adenovirus vector vaccine will be reviewed at a meeting of the FDA's Vaccines and Related Biological Products Advisory Committee later this week.

The ACIP recommends shared decision-making (SDM) for the 13-valent pneumococcal conjugate vaccine (PCV13) in adults older than 65 years, meningococcal B vaccination for adolescents and young adults aged 16–23 years, hepatitis B vaccination for adults older than 60 years with diabetes mellitus, and human papillomavirus vaccination for adults aged 27–45 years. According to its website, "Generally, ACIP makes shared clinical decision-making recommendations when individuals may benefit from vaccination, but broad vaccination of people in that group is unlikely to have population-level impacts." In a study published in the Journal of General Internal Medicine, researchers surveyed 617 primary care physicians recruited from the American College of Physicians and the American Academy of Family Physicians about their knowledge, attitudes, and experience with SDM vaccine recommendations. Most participants agreed that SDM requires more time than typical vaccine recommendations, is facilitated by specific talking points, can create confusion for patients, and may be difficult to implement. Compared to family physicians, general internists were more likely to report not knowing how to implement SDM recommendations as intended by the ACIP.

The February 1 issue of AFP included an article on targeted cancer therapies by Drs. Claire Smith and Vinayak Prasad. Targeted therapies may be monoclonal antibodies, small molecule inhibitors, antibody-drug conjugates, and/or immunotherapy. Immune checkpoint inhibitors (ICIs) - monoclonal antibodies that block inhibitory regulatory proteins and lead to T-cell activation - have a wide range of toxic effects on various organ systems, with thyroiditis being the most common. Family physicians should be aware of these potential adverse effects and their initial management in patients being treated with ICIs.

Finally, the AFP article mentioned the increasing financial toxicity of targeted cancer therapy:

In 2020, the average out-of-pocket cost to a patient for a course of oral cancer therapy was estimated at $5,663. According to one large analysis, 20% of patients with cancer take less medication than prescribed, 19% partially fill oral cancer therapy prescriptions, and 24% avoid filling a prescription at all. Many patients in this study reported spending less money on food, leisure, and clothing. Approximately 2% of patients will declare bankruptcy during their treatment; those with advanced disease are more likely to declare bankruptcy. Bankruptcy during cancer treatment increases the risk of death.

In a recent commentary in JAMA Internal Medicine, Dr. Prasad argued that the problem of unaffordability is compounded by the FDA's lenient approval process for new cancer drugs and subsequent mandatory Medicare coverage for approved drugs without price negotiation. Only a fraction of cancer drugs approved in the U.S. (often based on studies with surrogate end points rather than evidence of benefits in survival or quality of life) are approved for broad coverage in England and Canada. Not only is the clinical effectiveness of many of these drugs uncertain, but their value (cost-effectiveness) is questionable as well.

Monday, February 15, 2021

New(old) treatments for COVID: inhaled budesonide & the -umabs

 - Jennifer Middleton, MD, MPH

Although the Biden administration appears to be on track to meet its goal of 100 million COVID vaccines given in its first 100 days, the United States (US) is still unlikely to get most adults fully vaccinated before early 2022. With nearly 97,000 persons a day diagnosed with COVID-19 in the US last week, the need for effective COVID-19 treatment measures isn't going away any time soon. Researchers have identified two classes of medications that may benefit patients with symptomatic COVID-19, both well-known medications already in use for other conditions.

A small trial in the United Kingdom (UK) randomized 146 persons with mild COVID-19 to receive either inhaled budesonide (Pulmicort) or "usual care;" as with many COVID studies, this study's results have been publicized prior to full peer review and publication. The researchers used a composite end point of urgent care visit, emergency department visit, or hospitalization and found a number needed to treat of 8 to prevent 1 of those events. The small size of this trial may make it tempting to dismiss its findings, but as inhaled budesonide is generally well-tolerated and is relatively inexpensive, it still may be reasonable to use. Several other larger trials are currently underway evaluating inhaled budesonide, including the PRINICIPLE trial in the UK. 

Persons with more severe COVID-19 may benefit from tocilizumab or sarilumab, interleukin-6 receptor antagonists currently used for persons with rheumatoid arthritis. Last week, the UK's National Health Service informed its physicians that a trial randomizing 800 participants in intensive care for COVID which compared these two medications to usual care found that "[h]ospital mortality was 28.0% (98/350) for tocilizumab, 22.2% (10/45) for sarilumab and 35.8% (142/397) for [the] control [group]." Smaller trials had been less promising for this class of medications, though these studies were conducted earlier in the pandemic:

More studies will be needed to clarify when, and in which patients, tocilizumab and sarilumab work best, and to untangle why their benefits cropped up clearly in some studies, but not others.... It’s also challenging to compare studies coming out now to earlier trials that were conducted when the virus was much less understood, treatments were doled out with less know-how and mortality rates were even higher.

It remains to be seen whether the US Food and Drug Administration (FDA) and/or the Centers for Disease Control and Prevention (CDC) will follow the UK's lead and formally recommend these treatments for COVID-19, though it's heartening that research efforts continue to identify ways to lessen its burden. The AFP By Topic on Coronavirus Disease 2019 (COVID-19) has a section on "Treatment" which includes this Rapid Evidence Review of Outpatient Management of COVID-19 if you'd like to read more. 


Monday, February 8, 2021

Are primary care physicians overdiagnosing cutaneous melanoma?

 - Kenny Lin, MD, MPH

In an editorial in the February 1 issue of AFP, Dr. Jenny Doust and colleagues wrote about the problem of widening disease definitions, a common phenomenon in which the definition of a disease is "broadened over time to include milder and earlier cases," leading to harm "by exposing more patients to the adverse effects of treatments, triggering investigation and prescribing cascades, increasing anxiety, and placing a financial burden on patients and the wider society." Expanding the number of patients diagnosed with disease increases the burden on primary care physicians called on to manage these additional cases, even when it is uncertain if earlier interventions prevent morbidity or mortality. Illustrative examples of wider disease definitions include hypertension, polycystic ovary syndrome, breast cancer, and autism. What can family physicians do about it? The authors responded:

Recognizing the problem is the first step in tackling it. In particular, family physicians should not blindly accept new definitions and testing guidelines without an adequate understanding of the harms and benefits of the changes and the implications for our patients and wider practice.

Along similar lines, a recent analysis in the New England Journal of Medicine by Dr. H. Gilbert Welch and colleagues examined the drivers of the dramatically increased incidence of cutaneous melanoma in the U.S., which today is 6 times as high as in 1975 despite essentially no change in melanoma mortality. They pointed out that exposure to ultraviolent (UV) radiation (including tanning bed use) cannot account for more than a small portion of this increase. Instead, they argued that increased diagnostic scrutiny - "the combined effect of more screening skin examinations, falling clinical thresholds to biopsy pigmented lesions, and falling pathological thresholds to label the morphologic changes as cancer" - is most likely to be responsible for the epidemic of new diagnoses. Not only has the annual percentage of fee-for-service Medicare beneficiaries undergoing skin biopsies nearly doubled since 2004, but pathologists frequently upgraded skin biopsy specimens obtained in the late 1980s from benign to malignant when evaluating the same specimen two decades later. Primary care physicians contribute to widening the definition of cutaneous melanoma by performing or referring for biopsy small (<6 mm), incidentally detected skin lesions and screening patients with dermoscopy, which identifies more melanomas than visual inspection alone but is not well studied in primary care settings.

The U.S. Preventive Services Task Force (USPSTF) has concluded that current evidence is insufficient to assess the balance of benefits and harms of skin cancer screening in asymptomatic adults. Nonetheless, more than half of family physicians and general internists in a 2011 survey reported performing full-body skin examinations for skin cancer screening. In a 2020 AFP editorial, Drs. Michael Pignone and Adewole Adamson (Dr. Adamson also co-authored the NEJM analysis) observed that "compared with usual care, potential effects of screening on morbidity and mortality from keratinocyte carcinoma are at most small, and screening cannot be justified based on the impact on keratinocyte carcinoma alone." Dr. Welch and colleagues went one step further, arguing that the established harms of skin cancer screening already outweigh any potential benefits:

The increase in melanoma diagnoses by a factor of 6, with at least an order of magnitude more persons undergoing a biopsy and no apparent effect on mortality, is more than enough to recommend against population-wide screening. ... It [screening] has been effectively promoted under the guise of public health, with the combination of frightening messages about skin cancer and the premise that screening can only help. However, medical care should be driven by patient needs, not system needs. Now is not the time to add more anxiety and expense to an already anxious and expensive world.

Not surprisingly, dermatologists have a more positive view of skin cancer screening, as reported in a news story about the analysis by Dr. Welch and colleagues that quoted the president of the American Academy of Dermatology as stating that "an aggressive approach to prevention and treatment is entirely appropriate for a disease that kills 20 Americans each day." Of course, no one is urging clinicians to stop counseling patients on minimizing their exposure to UV radiation; indeed, the USPSTF recommends behavioral counseling to prevent skin cancer, particularly for children, their parents, and young adults. But screening for skin cancer, which has effectively widened the definition of cutaneous melanoma and driven widespread overdiagnosis - is a different story. To give Dr. Doust and colleagues the last word: "We [primary care physicians] are not here to passively enact specialist recommendations. Instead, we need to more assertively act as advocates for our patients and our communities."

Monday, February 1, 2021

COVID vaccine update: new data & new vaccines

 - Jennifer Middleton, MD, MPH

As challenges with distributing COVID-19 vaccines continue, additional data is emerging regarding the two mRNA vaccines already being given in the United States (US) along with Johnson & Johnson's Janssen vaccine and the Novavax vaccine. The Janssen and Novavax vaccines are likely to soon apply for Emergency Use Authorization.

Preliminary data out of Israel suggests that the Pfizer/BioNTech vaccine is even more effective than phase 3 trials in the US suggested. The Israeli Health Ministry announced last week "that of 428,000 Israelis who had received their second doses, only 63, or 0.014 percent, had contracted the virus." It's important to note that this data hasn't yet been subject to peer review or published, though the health fund gathering the data reportedly plans to do so very soon.

Johnson & Johnson also shared preliminary data from its Janssen vaccine international phase 3 trial last week. The Janssen vaccine uses an adenovirus vector to deliver the SARS-CoV-2 spike protein. They enrolled over 43,000 participants from the US, Latin America, and South Africa and found that:

Among all participants from different geographies and including those infected with an emerging viral variant, Janssen’s COVID-19 vaccine candidate was 66% effective overall in preventing moderate to severe COVID-19, 28 days after vaccination. The onset of protection was observed as early as day 14. 

Although these numbers are not as impressive as the Pfizer/BioNTech and NIH/Moderna vaccines, they still represent acceptable efficacy. Perhaps more importantly, the vaccine demonstrated "complete protection against COVID-related hospitalization and death," with none of the vaccinated participants experiencing hospitalization or death 28 days or more after vaccination. With the added bonuses of only requiring one vaccination and much simpler storage requirements (regular refrigeration), the Janssen vaccine may be an important addition to the COVID-19 pandemic arsenal. 

Lastly, the Novavax vaccine (NVX-CoV2373), which works via engineered spike proteins, is showing reasonable efficacy in trials in the United Kingdom (UK). Over 15,000 participants received the 2 doses of the Novavax vaccine in the UK:

The first interim analysis is based on 62 cases, of which 56 cases of COVID-19 were observed in the placebo group versus 6 cases observed in the NVX-CoV2373 group, resulting in a point estimate of vaccine efficacy of 89.3% (95% CI: 75.2 – 95.4). Of the 62 cases, 61 were mild or moderate, and 1 was severe (in placebo group).

"The newer, more contagious variant first identified in Britain was found to have caused about 50 percent of the cases in the trial, Novavax said.Phase 2b trials in South Africa have been less impressive, with only 60% efficacy (though with a very wide 95% confidence interval of 19.9-80.1), likely due to the South Africa SARA-CoV-2 variant. Novavax is already at work on another vaccine targeting this variant. Similar to the Janssen vaccine, the Novavax vaccine can be stored in a regular refrigerator

Assuming supply and distribution challenges are eventually overcome, vaccine hesitancy may pose another threat to decreasing SARS-CoV-2 transmission, which is critical to slowing the development of additional COVID variants. The Centers for Disease Control and Prevention (CDC) has resources and talking points to support clinicians with these conversations, and the AFP By Topic on Coronavirus Disease 2019 (COVID-19) also includes this article on "Helping Patients Make Healthy Decisions on COVID-19."

Tuesday, January 26, 2021

Aligning unhealthy drug use guidelines with evidence-based medicine

 - Kenny Lin, MD, MPH

According to a health advisory from the Centers for Disease Control and Prevention, drug overdose deaths increased substantially during the first few months of the COVID-19 pandemic, rising by a record 2,146 and 3,388 deaths from March to April and April to May 2020, respectively. Overall, "approximately 81,230 drug overdose deaths occurred in the United States in the 12 months ending in May 2020," with synthetic opioids, particularly illicit fentanyl, driving the increases. In response to this acceleration, last year the U.S. Preventive Task Force (USPSTF) for the first time recommended routine screening for unhealthy drug use in adults age 18 years and older, reasoning that identifying persons who are using illicit opioids, stimulants, cannabis, and other drugs would facilitate appropriate treatment. However, the American Academy of Family Physicians (AAFP), after reviewing the USPSTF's summary of the underlying evidence, determined that it did not support this sweeping recommendation. Instead, the AAFP issued an insufficient evidence statement on screening for all drugs except for opioid use disorder (OUD), and advised that clinicians screen adults selectively for OUD "after weighing the benefits and harms of screening and treatment."

In an editorial in the January 15th issue of AFP, Drs. Sarah Coles and Alexis Vosooney, members of the AAFP's Commission on the Health of the Public and Science (Dr. Coles is the current Chair of the Commission and an AFP contributing editor) explained their reasoning for disagreeing with the USPSTF. They noted that the originally commissioned USPSTF evidence report found that "for screen-identified populations, psychosocial interventions and pharmacotherapy do not improve drug use or the consequences." Although the USPSTF then requested a second report that found some effective interventions to reduce unhealthy drug use in treatment-seeking populations,

The AAFP believes that it was inappropriate to rely on this indirect evidence and to generalize the benefits of OUD treatment to screening and treatment of other substance use disorders [SUDs]. Readiness for treatment and availability of effective treatment modalities are key in the successful treatment of SUDs. These data prompted the AAFP to issue an insufficient evidence grade for screening for unhealthy drug use in adolescents and adults, except for OUD.

In an independent commentary that accompanied the publication of the USPSTF recommendation statement in JAMA, Dr. Richard Saltz made similar points in calling screening for unhealthy drug use "neither an unreasonable idea nor an evidence-based practice." Regarding the USPSTF's reliance on studies demonstrating benefits in treatment-seeking populations, he wrote:

Considering this latter set of studies that included patients seeking treatment for drug use is akin to considering studies of chemotherapy for patients seeking care for breast cancer or thrombolysis for symptomatic myocardial infarction as relevant to questions of cancer and cardiovascular disease screening efficacy; efficacious treatment is necessary but not sufficient for making a case for screening. ... Many patients identified with drug use by screening will not have any intention of changing their use of drugs and are not ready to begin treatment, whereas a patient seeking treatment is more ready for change and willing to begin treatment (the success of which relies on readiness and adherence).

Further, Dr. Saltz observed, "the applicability of both [USPSTF] reviews to primary care in the US ... may be limited because many studies were conducted in settings outside primary care; the good-quality studies in primary care settings were null." He also expressed concern that universal screening for unhealthy drug use in pregnant persons and documentation of such use, as the USPSTF advised, could cause considerable harm since nearly half of states consider drug use in pregnancy to be child abuse; in contrast, the only two studies of psychosocial counseling for unhealthy drug use in pregnancy found no benefits.

Lack of access to medication-assisted treatment with buprenorphine remains a significant problem for patients with OUD who desire it; a Graham Center One-Pager found that only 11% of psychiatrists and 2.4% of family physicians prescribed buprenorphine to Medicare beneficiaries between 2013 and 2016. In order to encourage more clinicians to treat OUD with evidence-based medications, the U.S. Department of Health and Human Services (HHS) recently announced that it would allow all outpatient physicians registered with the U.S. Drug Enforcement Administration, rather than only those with a Drug Addiction Treatment Act of 2000 or "X" waiver, to prescribe buprenorphine to up to 30 patients at one time. Unfortunately, the Biden administration is unlikely to implement the new guidelines due to concerns that HHS does not have the legal authority to override the act of Congress that established the "X" waiver process in the first place. For many communities devastated by the opioid overdose epidemic during the COVID-19 pandemic, the lack of accessible and affordable treatment for OUD may continue to be a barrier to care.

Monday, January 18, 2021

Do behavior therapy apps help people quit smoking?

 - Jennifer Middleton, MD, MPH

A common New Year's resolution is tobacco cessation, but for many patients, 2021 will be far from the first time they've tried to quit. Enter a new smartphone app, iCanQuit, which showed promising results in a recent study. Although there are some methodological concerns with the study's outcomes, this app may still be worth discussing with patients eager to improve their chances of finally quitting tobacco.

The researchers conducted a randomized, double-blind clinical trial comparing iCanQuit to the National Cancer Institute (NCI) QuitGuide app. The researchers recruited participants with online (primarily Facebook) advertisements; the mean age of participants was 38.2 years, and most (83%) had smoked for over 10 years. 70.4% of identified as female, and 35.9% identified as a member of a racial/ethnic minority group. Since all participants were enrolled and followed online only, the researchers took extra measures to ensure that responses were legitimate by requiring CAPTCHA authentication, monitoring IP addresses, and monitoring the time participants spent completing their online surveys. They enrolled 2415 participants who reported active tobacco smoking, provided the apps, and followed them for 12 months. 

Acceptance and commitment therapy (ACT), the theoretical underpinning for iCanQuit, emphasizes "acceptance of smoking triggers," while the NCI QuitGuide app emphasizes "avoidance of smoking triggers." 87% of participants stuck with the study for the entire 12 months; after that time, participants in the iCanQuit group were more likely to report having been smoke-free for 30 days prior (odds ratio 1.49; 95% confidence interval 1.22-1.83). There has been significant debate regarding the need for more objective measures (such as saliva or urine cotinine measurements) to validate self-reported cessation, but one of this study's shortcomings may be the impossibility of verifying these online participants' reports of smoking cessation. One argument supporting these participants' veracity, though, is their reported success rates; among all participants, 24.6% achieved 30-day cessation by the 12 month mark, while only 10.6% achieved "prolonged abstinence" (>30 day cessation). These rates are consistent with the success rates reported for several other tobacco cessation interventions

The use of apps to facilitate tobacco cessation is not new, but the evidence for their efficacy has room for improvement. A 2019 Cochrane review on mobile tobacco cessation programs found only low quality evidence for smartphone apps, though it found text-based smoking cessation programs to have modest efficacy. A 2020 systematic review that focused on smartphone apps found that:

The majority of studies that use tobacco cessation apps as an intervention delivery modality are mostly at the pilot/feasibility stage. The growing field has resulted in studies that varied in methodologies, study design, and inclusion criteria. More consistency in intervention components and larger randomized controlled trials are needed for tobacco cessation smartphone apps.

Tobacco smoking remains the "leading cause of preventable disease and death in the United States," and working with our patients to empower them to quit can have a tremendous impact on their health. Apps such as iCanQuit and the NCI QuitGuide may be another tool to share with patients. Check out the AFP By Topic on Tobacco Abuse and Dependence, which includes evidence-based overviews of several other cessation supports, if you'd like to read more. 

Sunday, January 10, 2021

Gender equity gaps persist in family medicine

 - Kenny Lin, MD, MPH

In a Graham Center Policy One-Pager in the January 1 issue of AFP, Dr. Yalda Jabbarpour and Elizabeth Wilkinson examined the growing role of women in family medicine. Compared to 2010, when 34% of practicing family physicians in the American Medical Association Physician Masterfile were identified as women, the share of women rose to 42% in 2020, mirroring increases in the share of female physicians in primary care and all medical specialties during the past decade. Another recent analysis by Dr. Jabbarpour and others found a statistically significant increase in female first and last authorship of research articles published in 3 family medicine journals (Family Medicine, Journal of the American Board of Family Medicine, and Annals of Family Medicine) between 2008 and 2017. However, they noted that women represented less than 40% of the combined editorial boards of these journals, which did not change significantly during this time.

A Graham Center study utilizing 2017 and 2018 certification survey data from the American Board of Family Medicine found that women self-reported working an average of 49 total hours and 34 direct patient care hours per week compared to 54 and 39 hours, respectively, self-reported by men. In an accompanying commentary on this "gender penalty," Dr. Kathryn Hart (an academic family physician colleague of mine) observed:

Traditional gender roles are still very much at play. The “invisible work” of raising children often falls on mothers, regardless of employment status. This begins with breastfeeding (and the natural carry-over to the intensive caregiving responsibilities of infancy) and evolves into scheduling doctor's appointments, completing school forms, coordinating activities, and arranging childcare, among thousands of other small tasks that cumulatively take up hours over the course of the week.

The work disparities that affect female-male dual professional couples have widened over the past year. The widespread transition to virtual learning from home during the COVID-19 pandemic has substantially increased the burdens of unpaid work (domestic chores and family care) that employed women perform relative to employed men worldwide.

Whether the physician gender pay gap can be attributed solely to female physicians working fewer hours than men was the subject of a recent analysis of data from more than 24 million primary care office visits in 2017. Despite spending 2.6% more observed time in visits overall than male primary care physicians, female primary care physicians conducted 10.8% fewer total visits and consequently generated 10.9% less revenue. Female physicians spent 15.7% more time (2.4 minutes) with each patient than male physicians did, but generated no more revenue per visit. In addition to the many other good reasons to retire the antiquated fee-for-service payment system in primary care, this study suggested that it remains an inherent obstacle to pay equity between male and female physicians.

Monday, January 4, 2021

Introducing Dr. Renee Crichlow, AFP's Medical Editor for Diversity, Equity, and Inclusion

 - Jennifer Middleton, MD, MPH

In AFP's first editorial of 2021, "Systemic Racism and Health Disparities: A Statement from Editors of Family Medicine Journals," the editors of several Family Medicine journals "commit to actively examine the effects of racism on society and health and to take action to eliminate structural racism in our editorial processes." AFP committed last year to "recruit editors and editorial board members from groups underrepresented in medicine," and please join us in welcoming AFP's new medical editor for Diversity, Equity, and Inclusion, Renee Crichlow, MD, FAAFP. Dr. Crichlow is the Director of Advocacy and Policy at the University of Minnesota School of Medicine where she holds the Mac Baird Endowed Chair in Family Medicine Advocacy and Policy. Here are some highlights from a recent interview!

1. Tell us a little about yourself and your background.

I grew up in the South, and I have lived on both coasts, the Mountain West, and the Midwest. I have seen communities and medical practice in many regions and I have come to realize that, first and foremost, I am a Family Medicine zealot. This country needs us. I have always practiced and taught full-spectrum care with Obstetrics having lived and worked in both rural and urban communities. I have known these communities as both a physician and a patient. When I gave birth to my son, I lived in a town of fewer than three thousand people and the hospital two blocks from our house had stopped doing deliveries a few years prior. I know personally what it means for a patient to drive sixty miles from home to have a safe delivery. I have done two fellowships, one at UCSF/UCDavis as a clinical research, faculty development fellow and the second through a Department of Health and Human Services Primary Care Health Policy Fellowship. As such, I believe that Family Medicine physicians working with their patients in the exam room is necessary for the health of our patients, and Family Medicine physicians working with health systems, stakeholders, and policymakers to develop evidence-based decisions is necessary for the health of our communities and the survival of our specialty.

2. What are your goals for this new position at AFP?

We aim to provide systemic support, including advising for authors and editors as we all engage with becoming an anti-racist, inclusive, and equitable specialty in our efforts to both care for and represent all of the communities we serve.

3. What advice might you share regarding specific actions each of us can take toward a more inclusive and equitable world?

First, do no harm, primum non nocere.

Second, ask yourself if you really care about anti-racism and inclusion and their impact on health equity. You may be comfortable with the current health inequities and prefer to attribute their causes to poor personal and individual choices. If not, you may care that the structures of current systems facilitate and perpetuate the status quo, a status quo that is inequitable to many of the patients and communities we serve. Third, consider this work more with a mindset of transformation than a change. The idea of change can seem very polarizing, e.g. light switch turns on the light, the light switch shuts off the light. That is categorical change and that type of change is not possible when dealing with anti-racism, inclusion, and equity, because the work that needs to be done has no predictable path; at its best, this process is co-creative where, working together, we all engage in transforming our systems to facilitate more inclusive and equitable outcomes.

4. Is there anything else you'd like AFP readers to know about you?

We are Family Medicine physicians. We deal with growth and change every day. I believe we are our best when we are helping each other grow through the challenges and choices of life, and these are indeed challenging times. Right now, our whole society is undergoing growth and change at an unprecedented pace. As with all growth, there will be some discomfort. We are Family Medicine physicians, trained to care for the full life cycle of our patients. We are not afraid of growth. I understand that, often, what people really fear is not change but loss. We understand that people may be concerned with changes where they will lose systems and structures that were familiar and dependable. But we know that the current systems and structures are inequitable for many and expensive and inefficient for all. I believe that addressing healthcare information and education using the lens of health equity and inclusion can contribute to systemic transformation. It provides a path for functional excellence, evidence-based structural revision, and systemic transformation.

Caring for all of our patients in an equitable and effective health system is a reasonable goal. We are Family Medicine. We can do this.